Ankylosing Spondylitis Infusion Centers

With local infusion centers across the country, Ankylosing Spondylitis patients requiring ongoing biologic infusions or injections relax in privacy and comfort during treatment.

Intentionally designed for Ankylosing Spondylitis patients.

Private Suites

Guaranteed for all patients, with leather recliners and chairs for guests

On Your Schedule

Local centers offer flexible scheduling, including evenings and weekends

Goodbye Waiting

Greeted by name at check-in, patient suites are always ready when you arrive

Sit Back and Relax

In-room streaming options so you can catch up on your favorite shows

Caring for those with Ankylosing Spondylitis.

Simply put, patients with Ankylosing Spondylitis who need ongoing infusion or injection treatment deserve better options for when, where and how they receive care.

Located in the communities where people live and work, IVX Health serves those with complex chronic conditions like Ankylosing Spondylitis by delivering high-quality, personalized care in a private, comfortable setting so patients can continue to live their best lives.

What is Ankylosing Spondylitis?

Ankylosing spondylitis is an inflammatory disease that over time can cause some of the bones in the spine to fuse. This fusing makes the spine less flexible and can result in a hunched posture. If ribs are affected, it can be difficult to breathe deeply.

How is Ankylosing Spondylitis Diagnosed and Treated?

Your doctor will be looking for signs of inflammation, tenderness, and limited range of motion in your spine and other joints. X-Rays and MRIs are also two common imaging tests used to help diagnose ankylosing spondylitis.

There is no cure for ankylosing spondylitis, but treatments can lessen symptoms and slow progression of the disease.

How Does IV Infusion Therapy for Ankylosing Spondylitis Work?

IV infusion for ankylosing spondylitis involves administering medication through an infusion pump that drips the medication into a catheter to a syringe and through a hollow needle into the patient’s bloodstream. IV infusion therapy options for ankylosing spondylitis include Simponi Aria and Remicade.

Some therapies, such as Cimzia, are administered via injection. Healthcare providers will use a needle to inject the drug subcutaneously into the front of the thighs or the abdomen. The initial doses are done in pairs every two weeks. Following the initial doses, maintenance doses are typically one injection every two weeks or two injections every four weeks. 

Many ankylosing spondylitis patients choose to get their IV infusion or injection treatment through a freestanding treatment center, such as IVX Health. Ankylosing Spondylitis patients often choose IVX Health as their preferred site of care because of its unique, patient-centered amenities, including private suites, its industry-leading 1:3 nurse-to-patient ratio, flexible appointment scheduling, and lower cost when compared to the hospital.

Ankylosing Spondylitis Therapies Administered at IVX Health

The following infusion and injection therapies are administered at IVX Health.

Ankylosing Spondylitis Management at IVX Health

Each IVX Health patient receives excellent care from Advanced Registered Nurse Practitioners (ARNPs) and Registered Nurses (RNs).

The benefits of receiving infusion treatments for ankylosing spondylitis at IVX Health include:

  • Private suites
  • Comfortable, leather recliners
  • Enough room and plenty of seating for guests
  • A friendly clinical staff
  • Personalized service
  • High-speed internet
  • Complimentary beverages and snacks
  • Flat-screen television sets provide a way for patients to stream their favorite movies and watch the shows they love
  • Flexible scheduling options (including evening and weekend appointments)

What to Expect During IV Infusion Treatment for Ankylosing Spondylitis

Step One

Using a thin, very small catheter, one of IVX Health’s nurses creates the patient an intravenous line (aka IV line) into the patient’s arm vein.

*For Cimzia, a subcutaneous injection, one of IVX Health’s nurses will inject the patient with the treatment typically in the front of the thighs or the abdomen. No IV line will be used.

Step Two

After placing the IV line, the nurse connects it to tubing that leads up to the medication. The medication is then dispersed into the patient’s bloodstream over a specified period of time.

During treatment, patients are continuously monitored by one of IVX’s nurses. If a patient requires assistance, he or she just needs to press the call button.

There are times when a patient experiences a reaction to the medication he or she is receiving; therefore, patients need to recognize the symptoms associated with an allergic reaction.

Signs of a potential allergic reaction include developing a headache, feeling nauseous, difficulty breathing and developing a rash. Patients experiencing these symptoms need to contact their nurse right away.

How to Get a Referral for Ankylosing Spondylitis IV Infusion or Injection Treatment

Every referral must be accompanied by an order for treatment.

Patient information should include:

  • Name
  • Current address
  • Home and mobile phone number
  • Insurance information

Information the physician must include on the patient’s order for IV therapy to treat TED include:

  • Patient’s name and DOB
  • Order date
  • Diagnosis
  • Physician’s name and NPI#
  • Office address, phone, and fax numbers
  • Provider’s signature

Supporting clinical documentation from the physician should include:

  • Results of a recent tuberculosis (TB) skin/lab testing
  • Patient’s current weight and height
  • Clinicals to support that the patient has active ankylosing spondylitis
  • For Remicade: Hepatitis B status and date

Due to the complexity of treatment, prior authorization is often required. Prior authorization is the process of getting approval for treatment from the patient’s healthcare provider before beginning treatment. It’s important to check in with your healthcare provider to see if a prior authorization will be needed for your infusion or injection treatment at IVX Health. 

If you have ankylosing spondylitis, and you would like to learn more about the IV infusion or injection therapy for ankylosing spondylitis available at IVX Health centers, contact us today.

What is Ankylosing Spondylitis?

Ankylosing spondylitis is a type of inflammatory arthritis that mainly impacts the axial spine, which includes the vertebrae in your neck and back. It can lead to inflammation in these vertebrae and, in some cases, the formation of new bone, resulting in chronic pain. For some, this condition may cause the vertebrae to fuse together, which can limit mobility. The term “ankylosing” refers to the stiffening of a joint, while “spondylitis” means inflammation of the vertebrae. Together, these words capture the unique challenges of this condition. It’s important to remember that ankylosing spondylitis can also bring other symptoms, such as fatigue and reduced lung capacity due to ribcage involvement. However, early diagnosis and proactive management can make a significant difference in improving your quality of life. You’re not alone, and with the right support, it’s possible to navigate this journey with greater ease.

What causes Ankylosing Spondylitis?

At the heart of Ankylosing Spondylitis (AS) risk is the presence of the HLA-B27 gene—a key player in our immune system’s orchestration. While not everyone carrying this gene develops AS, it is found in 90% of Caucasian patients diagnosed with the condition. The prevalence of HLA-B27 varies across different ethnic groups, spotlighting the importance of genetic predisposition in AS. For instance, this gene is less common in African and Asian populations, corresponding with a lower incidence of AS in these groups.

Immune System Dysfunction: AS represents a scenario where the immune system mistakenly turns against its tissues, particularly in the spine and sacroiliac joints. This leads to chronic inflammation, causing pain, stiffness, and, in severe cases, the fusion of vertebrae, significantly reducing flexibility and mobility. While the exact mechanisms behind this immune dysfunction are still being unraveled, it’s believed to involve a complex interplay of genetic and environmental factors. Together, we are dedicated to piecing this puzzle for a brighter, pain-free tomorrow.

Environmental Triggers: Certain infections or environmental factors may act as triggers for AS in genetically predisposed individuals. Although the exact environmental triggers remain a topic of ongoing research, some studies suggest that gut bacteria or other microbial agents might play a role. Additionally, lifestyle factors, such as smoking, have been linked to increased severity of AS, underlining that environmental influences cannot be overlooked in the disease’s progression. By understanding and addressing these triggers, we are committed to developing preventive strategies and enhancing treatment options, ensuring a healthier future for those at risk.

Symptoms of Ankylosing Spondylitis

Early signs of Ankylosing Spondylitis (AS) include chronic pain and stiffness in the lower back and hips, especially noticeable in the morning or after periods of inactivity. This discomfort can be persistent or intermittent, sometimes spreading to the buttocks and thighs. Unlike mechanical back pain, AS-related pain typically improves with exercise and worsens with rest, making physical activity a crucial part of symptom management. Some patients might also experience mild fever and fatigue during the early stages.

Progressive Symptoms: As the disease progresses, pain and stiffness can spread to other parts of the spine, including the neck, and even peripheral joints such as shoulders, knees, and ankles. This stage is characterized by more pronounced fatigue and unintentional weight loss, which can significantly impact daily life. Additionally, progressive symptoms might include eye inflammation (iritis or uveitis), causing pain, redness, and sensitivity to light. The disease’s systemic nature may lead to the involvement of other organs, adding complexity to its management.

Advanced Symptoms: In advanced stages, AS can lead to reduced flexibility and a hunched-forward posture due to spinal fusion, known as “bamboo spine.” This can severely limit mobility and make performing daily activities challenging. Breathing difficulties might arise due to the involvement of the rib cage, affecting lung expansion. Complications like vertebral fractures, which can occur even with minor trauma, and cardiovascular issues, such as aortitis and heart valve problems, may also develop. It’s essential to have comprehensive medical care and monitoring.

How to Diagnose Ankylosing Spondylitis

Physical Examination 

  • A thorough physical examination is the essential first step in diagnosing AS, focusing on tenderness, range of motion, and posture. During this examination, specific movements may be performed to identify any limitations or discomfort, while also checking for signs of inflammation or misalignment in the spine and other joints. Early diagnosis is crucial to prevent irreversible damage and improve long-term outcomes for you. Your well-being is our top priority! 

Imaging Tests

  • Imaging tests, including X-rays, MRI, and CT scans, play a vital role in diagnosing AS. X-rays reveal structural changes in the bones and joints, while MRI and CT scans provide more detailed images. These tests are invaluable in detecting inflammation, bone erosion, and new bone formation, characteristic of AS. MRI is especially useful for identifying active inflammatory lesions in the sacroiliac joints, often affected in the early stages of the disease. Advanced imaging techniques help monitor the progression of AS and assess the effectiveness of treatment.

Blood Tests 

  • Blood tests support the diagnosis by checking for markers of inflammation such as ESR (erythrocyte sedimentation rate) and CRP (C-reactive protein). Elevated levels of these markers indicate increased inflammation in the body, common in AS. Additionally, the presence of the HLA-B27 gene can be determined through blood tests, providing additional diagnostic information. Although not everyone with AS has the HLA-B27 gene, its presence can significantly increase the likelihood of an AS diagnosis. Blood tests may also be used to rule out other conditions that can cause similar symptoms, ensuring a more accurate diagnosis. We’re here to ensure you receive the most precise and compassionate care possible, because being known is being cared for. 

Standard Treatment Options for Ankylosing Spondylitis

While there is no cure for AS, various medications can help manage symptoms and improve quality of life. These treatments aim to reduce inflammation, alleviate pain, and slow the progression of the disease. Let’s explore some of the key medications used to treat AS, including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologics. Each of these medications plays a crucial role in helping patients lead more comfortable and active lives.

  1. NSAIDS: Nonsteroidal anti-inflammatory drugs (NSAIDs) are the first-line treatment to reduce inflammation and pain. Common NSAIDs include ibuprofen and naproxen.
  2. TNF Blockers: TNF blockers, such as infliximab, adalimumab, and etanercept, are biologics that reduce inflammation and halt disease progression. They are effective in managing moderate to severe AS.
  3. IL-17 Inhibitors: IL-17 inhibitors, like secukinumab and ixekizumab, offer an alternative to TNF blockers. These biologics target specific pathways involved in the inflammatory process.
  4. Physical therapy – exercise: Regular stretching and strengthening exercises are essential for maintaining flexibility and posture. Exercise helps reduce pain and improve overall well-being. posture training: Posture training techniques can help patients maintain good posture and prevent spinal deformities. Proper posture reduces stress on the spine and joints. hydrotherapy: or exercises performed in water, provides a low-impact way to improve flexibility and reduce strain on joints. It is particularly beneficial for patients with severe pain and stiffness.
  5. Surgical intervention: While surgical intervention is rarely needed, it may be considered for severe cases involving joint replacement or corrective surgery for spinal deformities.

Biologic Options for Ankylosing Spondylitis at IVX

While there is no cure for AS, various medications can help manage symptoms and improve quality of life. These treatments aim to reduce inflammation, alleviate pain, and slow the progression of the disease. Let’s explore some of the key medications used to treat AS, including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologics. Each of these medications plays a crucial role in helping patients lead more comfortable and active lives .

  • AVSOLA® (Infliximab-axxq): A powerful TNF blocker for those unresponsive to conventional therapies, reducing inflammation, improving joint function, and alleviating pain.
  • CIMZIA® (Certolizumab Pegol): A fast-acting TNF blocker that quickly reduces inflammation, alleviates pain and stiffness, and enhances overall mobility for those with active ankylosing spondylitis. 
  • INFLECTRA® (Infliximab-dyyb): A biosimilar to REMICADE®, offering similar benefits by reducing inflammation, alleviating pain, preventing joint damage, and enhancing physical function in AS patients. 
  • SIMPONI ARIA® (Golimumab): An infused biologic medication designed to target and neutralize TNF, effectively reducing inflammation and pain, improving physical function, and offering long-term relief from AS symptoms. 

Final Thoughts

Ankylosing spondylitis is a chronic inflammatory disease requiring a comprehensive management approach. Early diagnosis and treatment can significantly improve the quality of life and prevent severe complications. By understanding the causes, symptoms, pathophysiology, histopathology, and diagnostic methods, patients and healthcare professionals can work together to manage AS effectively.

For those newly diagnosed with AS, remember that you are not alone. Support networks, education, and proactive healthcare can make a significant difference in managing this condition. If you have any questions or need further assistance, don’t hesitate to reach out to your healthcare provider.

To explore more resources and stay updated on the latest research and therapies, consider joining our community of AS patients and healthcare professionals. Together, we can make a difference in the lives of those affected by ankylosing spondylitis. Let’s stay dedicated to providing the best patient care and creating a supportive, warm environment where everyone feels valued and cared for. Being known is being cared for, and we’re committed to making it happen every day!

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