Renflexis Infusion Therapy

See why thousands of patients choose our centers as their preferred destination for ongoing care, including Renflexis Infusion treatments.

Renflexis is a biologic therapy that is indicated to treat:

What Is Renflexis? 

Renflexis (infliximab-abda) is a prescription medication administered for patients in all IVX Health centers via IV infusion.  

Renflexis is a biosimilar of Remicade. A biosimilar is a biologic therapy that has been approved and licensed by the FDA and has shown to have no clinically meaningful difference from an existing therapy, known as the “reference product.” 

How Renflexis Works  

With certain health conditions, the immune system can overproduce a certain protein called tumor necrosis factor-alpha (TNF-alpha). Having too much TNF-alpha plays a role in the inflammation leading to some symptoms. Renflexis works by blocking the TNF-alpha actions and helps stop the underlying cause of inflammation. 

What Is Renflexis Used For?  

Doctors order infliximab-abda to treat several medical conditions. 

Renflexis treats: 

Renflexis Infusion Dosage and Administration  

Patients receive infliximab-abda intravenously. Treatment time for a Renflexis infusion at a medical clinic like IVX Health usually lasts around 2 hours. 

Dosage and Frequency  

Before receiving their first intravenous infusion of infliximab-abda, the ordering physician determines the patient’s dose. This dose depends on the patient’s weight as well as the severity of the condition for which he or she is receiving treatment. 

Renflexis is administered via infusion in three starting doses within the first six weeks of your treatment. After the initial six weeks, patients will receive infusions once every six-eight weeks or every four weeks for some RA patients. 

Administering Renflexis via IV Infusion  

  1. The nurse prepares the patient’s arm by using rubbing alcohol to sterilize the location that is being used to insert the IV needle. 
  2. Following needle insertion, the IV line is held in place with tape. 
  3. The nurse attaches the patient’s IV line to the line coming down from the bag of medication. 

Every half-an-hour, the patient’s nurse takes his or her vitals. 

Renflexis Infusion Side Effects  

As with all medications, side effects are possible.  

The most common side effects include: 

  • Respiratory infections, such as sinus infections and sore throat 
  • Headache 
  • Coughing 
  • Stomach pain 

Serious side effects include: 

  • Serious infections 
  • Heart failure 
  • Other heart problems 
  • Liver injury 
  • Blood problems 
  • Nervous system disorders 
  • Allergic reactions 
  • Lupus-like syndrome 
  • Psoriasis 

How To Prepare for a Renflexis Infusion  

Before starting Renflexis, patients should tell their doctor if they: 

  • Think they have an infection 
  • Are being treated for an infection 
  • Have signs of an infection 
  • Have any open cuts or sores on the body 
  • Get recurrent or a lot of infections 
  • Have diabetes or an immune system problem 
  • Have TB or have been in close contact with someone with TB 
  • Live or have lived in certain parts of the country where there is an increased risk of getting certain kinds of fungal infections 
  • Have or had Hepatitis B 
  • Use the medicines Kineret (anakinra) Orencia (abatacept), Actemra (tocilizumab) or other medicines called biologics used to treat the same conditions as Renflexis

How to Get a Referral for Renflexis IV Infusions  

Every Renflexis referral must be accompanied by a physician’s order for treatment. 

  • Patient information should include: 
  • Name 
  • Current address 
  • Home and mobile phone number 
  • Insurance information 

Information the physician must include on the patient’s order for Renflexis IV therapy: 

  • Patient’s name and DOB 
  • Order date 
  • Diagnosis 
  • Physician’s name and NPI# 
  • Office address, phone, and fax numbers 
  • Provider’s signature 

Supporting clinical documentation from the physician should include: 

Patients chose IVX Health to receive their ongoing Renflexis treatments because:

  • ALL private suites
  • Comfortable recliners, with chairs for guests
  • Evening & weekend appointments
  • Friendly clinical staff deliver personal service
  • Big screen TVs, high-speed WiFi, free snacks

Interested in moving your care to IVX Health?

Renflexis Financial Assistance Programs

Information about financial assistance programs coming soon.

Renflexis Related Blog Posts

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The infusion experience is a tough one. So to create this serene, peaceful environment means more than you will ever know.

Jennifer, Patient at IVX Health


IVX Health would love to learn more about your care needs. If you’re interested in switching your infusion services – or if you just want to learn more – let us know.