Truxima Infusion Therapy

See why thousands of patients choose our centers as their preferred destination for ongoing care, including Truxima Infusion treatments.

Truxima is a biologic therapy that is indicated to treat:

What Is Truxima? 

Truxima (rituximab-abbs) is a prescription medication administered for patients in all IVX Health centers via IV infusion. Additionally, Truxima is an FDA-approved biosimilar to Rituxan indicated to treat rheumatoid arthritis in adults. 

A biosimilar is a biologic therapy that has been approved and licensed by the FDA and has shown to have no clinically meaningful difference from an existing therapy, known as the “reference product.” 

How Truxima Works  

Truxima works by acting as an antibody that targets and reduces the number of B cells that are attacking bodily tissue in people with rheumatoid arthritis (RA). 

What Is Truxima Used For?  

Doctors order rituximab-abbs to treat: 

Truxima Infusion Dosage and Administration  

Patients receive rituximab-abbs intravenously. Treatment time for a Truxima infusion at a medical clinic like IVX Health usually lasts around 90 minutes. 


Before receiving their first intravenous infusion of rituximab-abbs, the ordering physician determines the patient’s dose. This dose depends on the patient’s weight as well as the severity of the condition for which he or she is receiving treatment. 

Administering Truxima via IV Infusion 

  1. The nurse prepares the patient’s arm by using rubbing alcohol to sterilize the location that is being used to insert the IV needle. 
  2. Following needle insertion, the IV line is held in place with tape. 
  3. The nurse attaches the patient’s IV line to the line coming down from the bag of medication. 

Every half-an-hour, the patient’s nurse takes his or her vitals.

Truxima Infusion Side Effects  

As with all medications, side effects are possible.  

Common side effects include: 

  • Infusion-related reactions 
  • Infections 
  • Body aches 
  • Tiredness 
  • Nausea 
  • Low red and white blood cell counts 
  • Swelling 
  • Diarrhea 
  • Muscle spams 
  • Aching joints during or within hours of receiving an infusion 
  • More frequent upper respiratory tract infection 

Serious side effects include: 

  • Serious infections  
  • Heart problems 
  • Kidney problems 
  • Stomach and serious bowel problems 
  • Tumor lysis syndrome (TLS) 
  • Severe skin and mouth reactions 
  • Progressive multifocal leukoencephalopathy (PML) 

How To Prepare for a Truxima Infusion  

It is essential that patients inform their physician if they currently have or have had: 

  • A severe reaction to Truxima or a rituximab product 
  • A history of heart problems, irregular heartbeat, or chest pain 
  • Lung or kidney products 
  • An infection or weakened immune system 
  • Any severe infections 

Patients should also inform their physician if they are currently taking any medicines, including prescription and over-the-counter medicines, vitamins, and herbal supplements. 

Before treatment, patients should get a good night’s sleep. In addition, they need to drink an adequate amount of fluid and eat a meal before their Truxima IV infusion treatment at IVX Health. 

During treatment with Truxima, patients need to avoid receiving live vaccines.

How to Get a Referral for Truxima IV Infusions  

Every Truxima referral must be accompanied by a physician’s order for treatment. 

  • Patient information should include: 
  • Name 
  • Current address 
  • Home and mobile phone number 
  • Insurance information 

Information the physician must include on the patient’s order for Truxima IV therapy: 

  • Patient’s name and DOB 
  • Order date 
  • Diagnosis 
  • Physician’s name and NPI# 
  • Office address, phone, and fax numbers 
  • Provider’s signature 

Supporting clinical documentation from the physician should include: 

  • Patient’s current weight and height 
  • Hepatitis B status & date 
  • Most recent CBC results 
  • Patient has moderately to severely active rheumatoid arthritis (RA) and is currently taking methotrexate 

If you or someone you care about has one of the conditions that Truxima infusions treat, you may want to learn more about IV infusion treatments with rituximab-abbs. To find an IVX Health infusion center near you, please click here. 

Patients chose IVX Health to receive their ongoing Truxima treatments because:

  • ALL private suites
  • Comfortable recliners, with chairs for guests
  • Evening & weekend appointments
  • Friendly clinical staff deliver personal service
  • Big screen TVs, high-speed WiFi, free snacks

Interested in moving your care to IVX Health?

Truxima Financial Assistance Programs

Information about financial assistance programs coming soon.

Truxima Related Blog Posts

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The infusion experience is a tough one. So to create this serene, peaceful environment means more than you will ever know.

Jennifer, Patient at IVX Health


IVX Health would love to learn more about your care needs. If you’re interested in switching your infusion services – or if you just want to learn more – let us know.

An IVX Health team member giving a blanket to a patient