Prolastin-C Infusion Therapy

See why thousands of patients choose our centers as their preferred destination for ongoing care, including Prolastin-C Infusion treatments.

Prolastin-C is a biologic therapy that is indicated to treat:

  • alpha 1 in adults — a rare genetic disease often known as “genetic COPD”

What Is Prolastin-C? 

Prolastin-C (alpha proteinase inhibitor) is a prescription medication administered for patients in all IVX Health centers via IV infusion.  

How Prolastin-C Works  

Prolastin-C works by raising levels of alpha1-proteinase inhibitor (alpha1-PI) that is missing or deficient in patients with alpha-1. 

What Is Prolastin-C Used For?  

Doctors order alpha proteinase inhibitor to treat: 

  • alpha 1 in adults — a rare genetic disease often known as “genetic COPD” 

Prolastin-C Infusion Dosage and Administration  

Patients receive alpha proteinase inhibitor intravenously. Treatment time for a Prolastin-C infusion at a medical clinic like IVX Health usually lasts around 15 minutes. 

Dosage and Frequency  

Before receiving their first intravenous infusion of Prolastin-C, the ordering physician determines the patient’s dose. This dose depends on the patient’s weight as well as the severity of the condition for which he or she is receiving treatment. 

Infusions of Prolastin-C are typically administered once per week. 

Administering Prolastin-C via IV Infusion  

  1. The nurse prepares the patient’s arm by using rubbing alcohol to sterilize the location that is being used to insert the IV needle. 
  2. Following needle insertion, the IV line is held in place with tape. 
  3. The nurse attaches the patient’s IV line to the line coming down from the bag of medication. 

Prolastin-C Infusion Side Effects  

As with all medications, side effects are possible. 

Common side effects include: 

  • Fatigue 
  • Diarrhea 
  • Allergic reaction 

How To Prepare for a Prolastin-C Infusion  

It is essential that patients inform their physician if they currently have, or have had, any of the conditions listed below: 

  • Allergies to any of the ingredients in Prolastin-C 
  • A severe or recurring infection 
  • Immunoglobulin A (IgA) deficiency 

How to Get a Referral for Prolastin-C IV Infusions  

Every Prolastin-C referral must be accompanied by a physician’s order for treatment. 

  • Patient information should include: 
  • Name 
  • Current address 
  • Home and mobile phone number 
  • Insurance information 

Information the physician must include on the patient’s order for Prolastin-C IV therapy: 

  • Patient’s name and DOB 
  • Order date 
  • Diagnosis 
  • Physician’s name and NPI# 
  • Office address, phone, and fax numbers 
  • Provider’s signature 

Supporting clinical documentation from the physician should include: 

  • Patient has shown clinical evidence of emphysema due to severe hereditary deficiency of Alpha-1 antitrypsin deficiency 

If you or someone you care about has one of the conditions that Prolastin-C infusions treat, you may want to learn more about IV infusion treatments with alpha proteinase inhibitor. To find an IVX Health infusion center near you, please click here. 

Patients chose IVX Health to receive their ongoing Prolastin-C treatments because:

  • ALL private suites
  • Comfortable recliners, with chairs for guests
  • Evening & weekend appointments
  • Friendly clinical staff deliver personal service
  • Big screen TVs, high-speed WiFi, free snacks

Interested in moving your care to IVX Health?

Prolastin-C Financial Assistance Programs

Information about financial assistance programs coming soon.

Prolastin-C Related Blog Posts

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The infusion experience is a tough one. So to create this serene, peaceful environment means more than you will ever know.

Jennifer, Patient at IVX Health


IVX Health would love to learn more about your care needs. If you’re interested in switching your infusion services – or if you just want to learn more – let us know.

An IVX Health team member giving a blanket to a patient