Nucala Injection Therapy

See why thousands of patients choose our centers as their preferred destination for ongoing care, including Nucala Injection treatments.

Nucala is a biologic therapy that is indicated to treat:

  • Add-on maintenance treatment of adult and pediatric patients aged 6 years and older with severe asthma and with an eosinophilic phenotype
  • Add-on maintenance treatment of adult patients 18 years and older withchronic rhinosinusitis with nasal polyps (CRSwNP)
  • The treatment of adult patients with eosinophilic granulomatosis with polyangiitis (EGPA)
  • The treatment of adult and pediatric patients aged 12 years and older with hypereosinophilic syndrome (HES) for ≥6 months without an identifiable non-hematologic secondary cause

What is Nucala?

What Is Nucala? 

Nucala (mepolizumab) is an injectable biologic monoclonal antibody used to treat patients with a variety of conditions, including severe eosinophilic asthma, eosinophilic granulomatosis with polyangiitis (EGPA), hypereosinophilic syndrome, and chronic rhinosinusitis with nasal polyps. 

How Nucala Works 

White blood cells called eosinophils make up a normal part of the body’s immune system. People with certain types of asthma can have too many eosinophils, leading to inflammation in the lungs and asthma attacks. 

Nucala works by reducing the number of eosinophils in the blood. 

Nucala Injection Dosage & Administration

Nucala Injection Dosage and Administration  

Patients receive Nucala via subcutaneous injection in the upper arm, thigh, or abdomen. 

Dosage and Frequency  

Typical dosage is 100mg/mL. 

Injections are typically administered once every four weeks. 

Nucala Side Effects

Nucala Injection Side Effects  

As with all medications, side effects are possible. 

Side effects include: 

  • Headache 
  • Injection site reactions  
  • Back pain 
  • Fatigue 
  • Allergic reactions

Preparing for Your Nucala Injection

Follow these steps to prepare for your Nucala Injection:

Consult Your Healthcare Provider

  • Medical History Review: Ensure your healthcare provider has a complete and up-to-date medical history, including any allergies, current medications, and past reactions to Injection.
  • Pre-Injection Testing: Complete any required blood tests or other pre-Injection tests as recommended by your healthcare provider.

Pre-Injection Medications

  • Prescription Pre-Medications: Your Nucala Injection may require pre-medications to reduce the risk of a reaction or adverse event. Your referring provider will include any pre-medications when sending in your prescription order.
  • Instructions: Follow your healthcare provider’s instructions regarding these medications, including the timing and dosage. Take these medications about 30-60 minutes before the Injection as directed.

Hydration and Nutrition

  • Hydrate: Drink plenty of water in the days leading up to your Injection to ensure you are well-hydrated.
  • Eat Light: Have a light meal before your Injection to help maintain your energy levels during the procedure.

Prepare for Comfort

  • Clothing: Wear loose, comfortable clothing with easy access to your arms for the Injection site.
  • Entertainment: Bring something to keep you occupied, such as a book, tablet, or music, as your treatment or observation period may take several hours.

Plan for Transportation

  • Arrange a Ride: Depending on the medication and your reaction to the Injection, you might not feel well enough to drive yourself home. Consider arranging for someone to drive you or use a ride service.

By following these steps, you can help ensure that your Nucala Injection is as safe and comfortable as possible. Always follow the specific instructions provided by your healthcare team.

How to Get a Referral for Nucala

Every Nucala Injection referral must be accompanied by a physician’s order for treatment.

Patient information should include:

  • Name
  • Current address
  • Home and mobile phone number
  • Insurance information

Information the physician must include on the patient’s order for therapy:

  • Patient’s name and DOB
  • Order date
  • Diagnosis
  • Physician’s name and NPI#
  • Office address, phone, and fax numbers
  • Provider’s signature

Clinical documentation from the physician should include information to support a diagnosis for one or more of the following:

  • Add-on maintenance treatment of adult and pediatric patients aged 6 years and older with severe asthma and with an eosinophilic phenotype
  • Add-on maintenance treatment of adult patients 18 years and older withchronic rhinosinusitis with nasal polyps (CRSwNP)
  • The treatment of adult patients with eosinophilic granulomatosis with polyangiitis (EGPA)
  • The treatment of adult and pediatric patients aged 12 years and older with hypereosinophilic syndrome (HES) for ≥6 months without an identifiable non-hematologic secondary cause

If you or someone you care about has one of the conditions that Nucala treats, IVX Health would be honored to provide your care. To find an IVX Health center near you, please click here.

Patients choose IVX Health for ongoing Nucala treatments because:

  • ALL private suites
  • Comfortable recliners, with chairs for guests
  • Evening & weekend appointments
  • Friendly clinical staff deliver personal service
  • Big screen TVs, high-speed WiFi, free snacks

Interested in moving your care to IVX Health?

Nucala Financial Assistance Programs

Information about financial assistance programs coming soon.

Nucala Related Blog Posts

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The infusion experience is a tough one. So to create this serene, peaceful environment means more than you will ever know.

Jennifer, Patient at IVX Health

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