Lumizyme Infusion Therapy

Lumizyme is a biologic therapy that is indicated to treat:

• Pompe disease

What Is Lumizyme?  

Lumizyme (alglucosidase alfa) is a prescription enzyme replacement therapy administered for patients in all IVX Health centers via IV infusion. 

How Lumizyme Works  

 Lumizyme works by replacing a missing or deficient enzyme called acid α-glucosidase (GAA) in patients with Pompe disease. 

What Is Lumizyme Used For?  

Doctors order alglucosidase alfa to treat: 

• Pompe disease 

Lumizyme Infusion Dosage and Administration  

Patients receive alglucosidase alfa intravenously. Treatment time for a Lumizyme infusion at a medical clinic like IVX Health usually lasts for around four hours. 

Dosage and Frequency  

Before receiving their first intravenous infusion of alglucosidase alfa, the ordering physician determines the patient’s dose. This dose depends on the patient’s weight as well as the severity of the condition for which he or she is receiving treatment. 

Doses are typically administered once every two weeks. 

Administering Lumizyme via IV Infusion  

1.  The nurse prepares the patient’s arm by using rubbing alcohol to sterilize the location that is being used to insert the IV needle. 
2. Following needle insertion, the IV line is held in place with tape. 
3. The nurse attaches the patient’s IV line to the line coming down from the bag of medication. 

Every half-an-hour, the patient’s nurse takes his or her vitals. 

Lumizyme Infusion Side Effects  

As with all medications, side effects are possible.  

Side effects include: 

• Severe allergic reactions and hypersensitivity 
• Skin-related and other immune system-related reactions 
• Risk of worsening heart or lung function 
• Development of IgG antibodies 

 To decrease the likelihood of the patient experiencing another reaction, he or she may be advised to take certain medications before the next IV infusion treatment with alglucosidase alfa. 

How To Prepare for a Lumizyme Infusion  

It is essential that patients inform their physician if they currently have, or have had, any of the conditions listed below: 

• Allergies to any of the ingredients in Lumizyme 
• Heart or lung problems 
• Active infection or recurring infections 

Before treatment, patients should get a good night’s sleep. In addition, they need to drink an adequate amount of fluid and eat a meal before their Lumizyme IV infusion treatment at IVX Health. 

How to Get a Referral for Lumizyme IV Infusions  

Every Lumizyme referral must be accompanied by a physician’s order for treatment. 

• Patient information should include: 
• Name 
• Current address 
• Home and mobile phone number 
• Insurance information 

Information the physician must include on the patient’s order for Lumizyme IV therapy: 

• Patient’s name and DOB 
• Order date 
• Diagnosis 
• Physician’s name and NPI# 
• Office address, phone, and fax numbers 
• Provider’s signature 

Supporting clinical documentation from the physician should include: 

• Patient is 8 years and older with late (non-infantile) onset Pompe disease (GAA deficiency) who has no evidence of cardiac hypertrophy 

If you or someone you care about has one of the conditions that Lumizyme infusions treat, you may want to learn more about IV infusion treatments with alglucosidase alfa. To find an IVX Health infusion center near you, please click here. 

Patients chose IVX Health to receive their ongoing Lumizyme treatments because:

• ALL private suites
• Comfortable recliners, with chairs for guests
• Evening & weekend appointments
• Friendly clinical staff deliver personal service
• Big screen TVs, high-speed WiFi, free snacks