Krystexxa Infusion Therapy

See why thousands of patients choose our centers as their preferred destination for ongoing care, including Krystexxa Infusion treatments.

Krystexxa is a biologic therapy that is indicated to treat:

  • chronic gout in adults who haven’t responded to other therapies

What is Krystexxa?

What Is Krystexxa? 

Krystexxa (pegloticase) is a prescription medication administered for patients in all IVX Health centers via IV infusion to help reduce symptoms of gout. 

How Krystexxa Works  

In patients with gout, uric acid builds up in the joints, causing the symptoms of the disease. Krystexxa works by lowering uric acid levels in the body and removing uric acid crystal buildup in the joints. 

Krystexxa Infusion Dosage & Administration

Krystexxa Infusion Dosage and Administration  

Patients receive pegloticase intravenously. Treatment time for a Krystexxa infusion at a medical clinic like IVX Health usually lasts roughly two hours. 

Dosage and Frequency  

Typical dosage of Krystexxa is 8 mg/mL.  

Krystexxa is generally administered once every two weeks. 

Administering Krystexxa via IV Infusion  

  1. The nurse prepares the patient’s arm by using rubbing alcohol to sterilize the location that is being used to insert the IV needle. 
  2. Following needle insertion, the IV line is held in place with tape. 
  3. The nurse attaches the patient’s IV line to the line coming down from the bag of medication. 

Every half-an-hour, the patient’s nurse takes his or her vitals.

Krystexxa Side Effects

Krystexxa Infusion Side Effects  

As with all medications, side effects are possible. 

Common side effects of Krystexxa include: 

  • Gout flare-ups or attacks 
  • Allergic reactions 
  • Nausea 
  • Bruising 
  • Sore throat 
  • Constipation 
  • Chest pain 
  • Vomiting  

Patients should inform their referring physician if they experience serious side effects. 

Serious side effects include: 

  • Wheezing, shortness of breath, or coughing 
  • Chest tightness or trouble breathing 
  • Reddening of the face 
  • Itching 
  • Hives 
  • Feeling warm 
  • Swelling of the throat or tongue 
  • Throat tightness 
  • Hoarse voice 
  • Trouble swallowing 

Preparing for Your Krystexxa Infusion

Follow these steps to prepare for your Krystexxa Infusion:

Consult Your Healthcare Provider

  • Medical History Review: Ensure your healthcare provider has a complete and up-to-date medical history, including any allergies, current medications, and past reactions to Infusion.
  • Pre-Infusion Testing: Complete any required blood tests or other pre-Infusion tests as recommended by your healthcare provider.

Pre-Infusion Medications

  • Prescription Pre-Medications: Your Krystexxa Infusion may require pre-medications to reduce the risk of a reaction or adverse event. Your referring provider will include any pre-medications when sending in your prescription order.
  • Instructions: Follow your healthcare provider’s instructions regarding these medications, including the timing and dosage. Take these medications about 30-60 minutes before the Infusion as directed.

Hydration and Nutrition

  • Hydrate: Drink plenty of water in the days leading up to your Infusion to ensure you are well-hydrated.
  • Eat Light: Have a light meal before your Infusion to help maintain your energy levels during the procedure.

Prepare for Comfort

  • Clothing: Wear loose, comfortable clothing with easy access to your arms for the Infusion site.
  • Entertainment: Bring something to keep you occupied, such as a book, tablet, or music, as your treatment or observation period may take several hours.

Plan for Transportation

  • Arrange a Ride: Depending on the medication and your reaction to the Infusion, you might not feel well enough to drive yourself home. Consider arranging for someone to drive you or use a ride service.

By following these steps, you can help ensure that your Krystexxa Infusion is as safe and comfortable as possible. Always follow the specific instructions provided by your healthcare team.

How to Get a Referral for Krystexxa

Every Krystexxa Infusion referral must be accompanied by a physician’s order for treatment.

Patient information should include:

  • Name
  • Current address
  • Home and mobile phone number
  • Insurance information

Information the physician must include on the patient’s order for therapy:

  • Patient’s name and DOB
  • Order date
  • Diagnosis
  • Physician’s name and NPI#
  • Office address, phone, and fax numbers
  • Provider’s signature

Clinical documentation from the physician should include information to support a diagnosis for one or more of the following:

  • chronic gout in adults who haven’t responded to other therapies

If you or someone you care about has one of the conditions that Krystexxa treats, IVX Health would be honored to provide your care. To find an IVX Health center near you, please click here.

Patients choose IVX Health for ongoing Krystexxa treatments because:

  • ALL private suites
  • Comfortable recliners, with chairs for guests
  • Evening & weekend appointments
  • Friendly clinical staff deliver personal service
  • Big screen TVs, high-speed WiFi, free snacks

Interested in moving your care to IVX Health?

Krystexxa Financial Assistance Programs

Information about financial assistance programs coming soon.

Krystexxa Related Blog Posts

No results found.

The infusion experience is a tough one. So to create this serene, peaceful environment means more than you will ever know.

Jennifer, Patient at IVX Health

Interested?

IVX Health would love to learn more about your care needs. If you’re interested in switching your infusion services – or if you just want to learn more – let us know.

An IVX Health team member giving a blanket to a patient