Fabrazyme Infusion Therapy

Fabrazyme is a biologic therapy that is indicated to treat:

• Adult and pediatric patients 2 years of age and older with confirmed Fabry disease

What Is Fabrazyme? 

Fabrazyme (agalsidase beta) is a prescription biologic medication administered for patients in all IVX Health centers via IV infusion. 

How Fabrazyme Works  

Fabrazyme is an enzyme replacement therapy (ERT) that supplies the body with the enzyme that is missing or deficient in patients with Fabry disease. This missing or deficient enzyme typically clears GL-3 buildup in cells. For people with Fabry disease taking Fabrazyme, the therapy replaces these enzymes in order to clear GL-3 buildup. 

What Is Fabrazyme Used For?  

Doctors order agalsidase beta to treat: 

• Adult and pediatric patients 2 years of age and older with confirmed Fabry disease 

Fabrazyme Infusion Dosage and Administration  

Patients receive agalsidase beta intravenously. Treatment time for a Fabrazyme infusion at a medical clinic like IVX Health usually lasts between two to three hours. 

Dosage and Frequency  

Before receiving their first intravenous infusion of agalsidase beta, the ordering physician determines the patient’s dose. This dose depends on the patient’s weight as well as the severity of the condition for which he or she is receiving treatment. 

Fabrazyme infusions are usually administered every two weeks. 

Administering Fabrazyme via IV Infusion  

1. The nurse prepares the patient’s arm by using rubbing alcohol to sterilize the location that is being used to insert the IV needle. 
2. Following needle insertion, the IV line is held in place with tape. 
3. The nurse attaches the patient’s IV line to the line coming down from the bag of medication. 

Every half-an-hour, the patient’s nurse takes his or her vitals. 

Fabrazyme Infusion Side Effects  

As with all medications,  side effects are possible.  

Common side effects include: 

• Upper respiratory tract infection 
• Chills 
• Fever 
• Headache 
• Cough 
• Burning and/or tingling sensation 
• Fatigue 
• Swelling in the legs 
• Dizziness 
• Rash  
• Allergic reactions  

While receiving Fabrazyme, or following a treatment, symptoms can be addressed with the appropriate medication (such as acetaminophen, steroids, antihistamines, or epinephrine). 

How To Prepare for a Fabrazyme Infusion  

It is essential that patients inform their physician if they currently have, or have had, any of the conditions listed below: 

• Heart problems 
• Allergies to the ingredients in Fabrazyme 

Before treatment, patients should get a good night’s sleep. In addition, they need to drink an adequate amount of fluid and eat a meal before their Fabrazyme IV infusion treatment at IVX Health. 

How to Get a Referral for Fabrazyme IV Infusions  

Every Fabrazyme referral must be accompanied by a physician’s order for treatment. 

• Patient information should include: 
• Name 
• Current address 
• Home and mobile phone number 
• Insurance information 

Information the physician must include on the patient’s order for Fabrazyme IV therapy: 

• Patient’s name and DOB 
• Order date 
• Diagnosis 
• Physician’s name and NPI# 
• Office address, phone, and fax numbers 
• Provider’s signature 

Supporting clinical documentation from the physician should include: 

• Clinicals to support that the patient has Fabry disease 

If you or someone you care about has one of the conditions that Fabrazyme infusions treat, you may want to learn more about IV infusion treatments with agalsidase beta. To find an IVX Health infusion center near you, please click here. 

Patients chose IVX Health to receive their ongoing Fabrazyme treatments because:

• ALL private suites
• Comfortable recliners, with chairs for guests
• Evening & weekend appointments
• Friendly clinical staff deliver personal service
• Big screen TVs, high-speed WiFi, free snacks